Ultra Low Temperature Freezers
w T-150 Ultra Low Temp Freezer (-150 C) w B-120 Blast Freezer (120 Liter Load) w T-90 Low Temp Freezer (-90 C)
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About Cryometrix
About Cryometrix Cryometrix develops, manufactures and markets refrigeration and cryogenic preservation equipment. The Ultra Low Temperature model T-150 is an "all in one" +20C to -150C cryogenic freezing system. It is the first liquid nitrogen based, programmable cryogenic freezing system in a standard upright format, which allows for exceptional reliability, precise thermal uniformity, and no user or product exposure to liquid nitrogen. The Cryometrix freezer is optimized for bio-repositories, research, forensic, hospitals, clinical laboratories and other life science applications where refrigeration and cryogenic preservation is required. With the success of the T-150 we have been able to answer the needs of our customers by introducing two new cryogenic freezers. The T-90 is our low temperature freezer having a temperature range +20C to -90C. Our B-120 Blast Freezer with a temperature range of +20C to -100C allows for rapid freezing of up to 120 liters of product within 24 hours or less. Cryometrix Advantage Cryometrix freezers can be mapped into an FDA regulated environment; they consume less floor space (one Cryometrix freezer can replace up to five mechanical freezers for the same footprint). They can also serve as a shipping container that meets an important need for Cold Chain Management. Cryometrix freezers can maintain temperature without power for days. There are many patents interwoven within the freezer designs with 10 patents either issued or published. By using these patented technologies, users can look forward to virtually eliminating electrical consumption; this may help eliminate the need to construct expansive new facilities to grow production and reduce operational costs. The average life of our Cryometrix freezer is estimated to be over 25 years, up to five times longer than an old technology mechanical freezer. Case studies of installations at major pharmaceutical companies and governmental/military agencies demonstrate the success of these technologies in real world applications and installations. Please review the following pages describing in detail our cryogenic freezers and we think you will agree that we have the Cryometrix Ultra Low Temperature Advantage.
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T-150 Ultra Low Temp Freezer
T-150 Ultra Low Temp Freezer (-150 C)
The T-150 programmable ULT freezer delivers on all points. The T-150 freezer is a technological breakthrough that incorporates a patented compressor-free, redundant, mission critical liquid nitrogen-based technology. The T-150 is a stable, scalable, adaptable, and validatable platform. The payload capacity is 21.25 ft3 (600 L = 30,000 2-mL vials), and with its all-stainless steel upright design, the T-150 resolves several user issues common to traditional mechanical systems such as security issues, complicated operation, cleaning, and icing. The T-150 features a system that is easy to use, easy to clean, increases productivity, and eliminates icing.
T-150 Performance
No compressors No harmful refrigerants used Very low operating costs Temperature uniformity, reliability, and validation are key to what life scientists are searching for in an ultra low temperature (ULT) freezer. The T-150 provides a quantum leap forward in cryopreservation technology. Additional management issues such as a considerable reduction in net operating costs, better use of available laboratory floor space, significant reduction in electrical power use, and the elimination of CFCs (chlorofluorocarbons) have become the governing principles of laboratory managers. With up to 90% less electrical consumption, the T-150 reduces annual electrical use by over 34,000 kilowatts per freezer, per year at a setpoint of -86C through efficient design, the elimination of refrigeration compressors, and the required HVAC component. Thermal stability and freezer reliability are key factors when it comes to cryopreservation. The T-150 accomplishes both through the use of CoLD technologies, which yield temperature uniformity of 3C. Temperature recovery from an open/close event is less than 10 minutes with a T of 5C.
Thermal stability during a ramp to setpoint is key for sensitive sample survival. Degradation of vials due to rapid thermal shock is prevented using the programmable control of the T-150. A precise ramp rate of up to 3.5C/minute can be programmed by the user. The T-150 has a MTBF (mean time between failures) of three years, with the only preventative maintenance being the calibration of temperature and pressure sensors, all of which can be completed while the freezer is in operation. The T-150 has received several patents for its insulation, liquid control, and upright design. This is a recognition of the truly unique and innovative design elements of the T-150.
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T-150 Ultra Low Temp Freezer
Features
Unique Contained Liquid Nitrogen Delivery (CoLD) technology Excellent thermal performance Fast controllable temperature ramp Uniform temperatures throughout payload bay ( 3C) Fast recovery from open/close event (<10 min) Large 21.25 ft.3/ 600 liters storage volume 30,000 x 2ml vial storage capacity controlled at 3C Customized racking available Compressor free operation Minimal power consumption No rejected heat into workspace Essentially noiseless operation, vibration and dust free Low LN2 consumption Mission critical design Redundant circuits assure reliability User security features Low maintenance design Ergonomically simplified design As easy to use as a common household refrigerator Left or right hand door swing
Benefits
Designed for cGMP applications DQ/IQ completed OQ/PQ ready GMP qualified units currently in PharmBio use Compared to compressor based technologies - The T-150 offers: A significant reduction in electrical power consumption Up to 5 times greater payload capacity per unit area of floor space Significant overall reduction in net operating expenses No liquid nitrogen exposure to users or product
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T-150 Ultra Low Temp Freezer
Specifications:
Dimensions Weight 74" x 45" x 38" Empty - 1243 lbs. Gross Weight Allowable - 2068 lbs. 21.25 ft.3 375 lbs. (5 shelf) 825 lbs. (15 shelf) 500 Watts Max LN2 - Capable of -175C within 5 minutes 18-90 PSI +20C to -150C 3C -1 to -3 C/min -80 C <0.26 gallons/hr -150 C <0.79 gallons/hr
Payload Electrical Cooling Media Inlet Pressure Service Temperature Temperature Uniformity Ramp Rate Liquid Nitrogen Consumption
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B-120 Blast Freezer
B-120 Blast Freezer (120 Liter Load Capacity)
The B-120 programmable blast freezer delivers a technological breakthrough that incorporates a compressor-free, liquid nitrogen-based technology that can freeze up to 36 times faster than a mechanical freezer system. The B-120 is a stable, scalable, adaptable, and validatable platform. The payload capacity is 21.25 ft3 (load capacity is (12) 10 liter bottles or equivalent in a single batch cycle). With its all-stainless steel upright design, the B-120 resolves several user issues common to traditional mechanical systems such as security issues, complicated operation, cleaning, and icing. The B-120 Blast Freezer features a system that is easy to use, easy to clean, increases productivity, and eliminates icing.
B-120 Performance
Up to 36 times increase in product throughput No compressors, no downtime No harmful refrigerants used Thermal performance, reliability, and validation are key to what life scientists are searching for in any cryoprocessor. The B-120 provides a quantum leap forward in cryoprocessing technology. Additional management issues such as exceptional increase in product throughput resulting in floor space utilization improvements, a considerable reduction in net operating costs, significant reduction in electrical power use, dramatic increase in uptime and the elimination of CFCs (chlorofluorocarbons) have become the governing principles of laboratory managers. With up to 90% less electrical consumption, the B-120 reduces annual electrical use by over 34,000 kilowatts per unit, per year at a setpoint of -86C through efficient design, elimination of refrigeration compressors, and elimination of required HVAC components needed for mechanical freezers. When it comes to uptime and reliability, the B-120 is in a league of its own through the use of Contained Liquid Delivery (CoLD) technologies which eliminate all compressors and failure prone components. The required maintenance requirements are reduced significantly per installed unit. With the B-120, what used to be a team of repair technicians is now just one preventative maintenance technician, no matter the size of the facility. Thermal stability and freezer reliability are key factors when it comes to cryopreservation. The B-120 accomplishes both through the use of CoLD technologies, which yield a 36X increase in product throughput. In-situ thermal mapping provides for extremely accurate thermal processing without compromising performance of either process or machine. A CISS technology inventory system allows users to adapt the B-120 to any product container, bag, or process device. Thermal stability during a ramp to setpoint is key for sensitive sample survival. Degradation of vials due to rapid thermal shock, or protein sublimation is prevented using the programmable control of the B-120. With the T-150 ULT Freezer, the matriarch of the product line, having over 1 million field operational hours, the B-120 has a MTBF (mean time between failures) of three years, with the only preventative maintenance being the calibration of temperature and pressure sensors, all of which can be completed while the cryoprocessor is in operation.
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B-120 Blast Freezer
Features
Unique Contained Liquid Nitrogen Delivery (CoLD) technology Fast controllable temperature ramp Uniform temperatures throughout payload bay ( 3C) Large 21.25 ft.3 (load capacity is (12) 10 liter bottles or equivalent in a single batch cycle) Customized racking available Compressor free operation Minimal power consumption No rejected heat into workspace Essentially noiseless operation, vibration and dust free Low LN2 consumption Mission critical design User security features Low maintenance design Ergonomically simplified design As easy to use as a common household refrigerator
Benefits
Designed for cGMP applications DQ/IQ completed OQ/PQ ready GMP qualified units currently in PharmBio use Compared to compressor based technologies - The B-120 offers: Up to 36X faster freezing than other freezers A significant reduction in electrical power consumption Up to 5 times greater payload capacity per unit area of floor space Significant overall reduction in net operating expenses No liquid nitrogen exposure to users or product
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B-120 Blast Freezer
Specifications:
Dimensions Weight 74" x 45" x 38" Empty - 1243 lbs. Gross Weight Allowable - 2068 lbs. 21.25 ft.3 (load capacity is (12) 10 liter bottles or equivalent) 375 lbs. (5 shelf) 825 lbs. (15 shelf) 500 Watts Max LN2 - Capable of -175C within 5 minutes 18-90 PSI +20C to -100C 3C 120 Liters of aqueous solution 22 hours 175 Gallons
Payload Electrical Cooling Media Inlet Pressure Service Temperature Temperature Uniformity Ramp Rate (ambient to -80C) Liquid Nitrogen Consumption (ambient to -80C)
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T-90 Low Temp Freezer
T-90 Low Temp Freezer (-90 C)
The T-90 programmable ULT freezer delivers on all points. The T-90 freezer is a technological breakthrough that replaces traditional mechanical freezers by incorporating a compressor-free, liquid nitrogen-based technology. The T-90 is a stable, scalable, adaptable, and validatable platform. The payload capacity is 21.25 ft3 (600 L = 30,000 2-mL vials), and with its all-stainless steel upright design, the T-90 addresses the two users complaints of mechanical freezers, icing and reliability. The T-90 offers security, ease of operation, ease of cleaning, and a system that has patented technology designed to eliminate icing.
T-90 Performance
No compressors No harmful refrigerants used Very low operating costs Temperature uniformity, reliability, and validation are key to what life scientists are searching for in an ultra low temperature (ULT) freezer. The T-90 provides a quantum leap forward in cryopreservation technology. Additional management issues such as a lab noise elimination, considerable reduction in net operating costs through the elimination of rejected heat into the lab requiring additional HVAC, better use of available laboratory floor space, significant reduction in electrical power use, and the elimination of CFCs (chlorofluorocarbons) have become the governing principles of laboratory managers. With up to 90% less electrical consumption, the T-90 reduces annual electrical use by over 34,000 kilowatts per freezer, per year at a setpoint of -86C through efficient design, the elimination of refrigeration compressors, and the required HVAC component. Thermal stability and freezer reliability are key factors when it comes to cryopreservation. The T-90 accomplishes both through the use of CoLD technologies, which yield temperature uniformity of 3C. Temperature recovery from an open/close event is less than 10 minutes.
The T-90 has a MTBF (mean time between failures) of over three years, with the only preventative maintenance being the calibration of temperature and pressure sensors, all of which can be completed while the freezer is in operation. This is demonstrated by the matriarch for the Cryometrix family, the T-150, which is approaching 2 million operational hours on the installed fleet. There have been only three component failures resulting in zero system downtime.
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T-90 Low Temp Freezer
Features
Unique Contained Liquid Nitrogen Delivery (CoLD) technology Excellent thermal performance Fast controllable temperature ramp Uniform temperatures throughout payload bay ( 3C) Fast recovery from open/close event (10 min) Large 21.25 ft.3 / 600 liters storage volume 30,000 x 2ml vial storage capacity controlled at 3C Customized racking available In-situ user port allows thermal probe installation into the payload bay with out compromising door seals or the frequent user installed thru port on mechanical freezers. Compressor free operation Minimal power consumption No rejected heat into workspace Essentially noiseless operation, vibration and dust free Ergonomically simplified design As easy to use as a common household refrigerator User maintenance is a sweeping of power-like snow during open/close events Low LN2 consumption Requiring approximately the same dollar value in LN2 as electrical power for the traditional mechanical freezer in sustaining mode operation Highly reliable, patented liquid delivery technology meters LN2 to minimize LN2 consumption
Benefits
Designed for cGMP applications DQ/IQ completed OQ/PQ ready GMP qualified units currently in PharmBio use Compared to compressor based technologies - The T-90 offers: A significant reduction in electrical power consumption Up to 5 times greater payload capacity per unit area of floor space Significant overall reduction in net operating expenses No liquid nitrogen exposure to users or product
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T-90 Low Temp Freezer
Specifications:
Dimensions Weight 74" x 45" x 38" Empty - 1243 lbs. Gross Weight Allowable - 2068 lbs. 21.25 ft.3 375 lbs. (5 shelf) 825 lbs. (15 shelf) 500 Watts Max LN2 - Capable of -175C within 5 minutes 18-90 PSI +20C to -90C 3C < 0.4 gallons/hr
Payload Electrical Cooling Media Inlet Pressure Service Temperature Temperature Uniformity Liquid Nitrogen Consumption (Steady State = -90C)
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