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. 2017 Apr 8;9(10):503-509.
doi: 10.4254/wjh.v9.i10.503.

Egg consumption and risk of non-alcoholic fatty liver disease

Zeinab Mokhtari  1 , Hossein Poustchi  1 , Tannaz Eslamparast  1 , Azita Hekmatdoost  1
Affiliations

Egg consumption and risk of non-alcoholic fatty liver disease

Zeinab Mokhtari et al. World J Hepatol. .

Abstract

Aim: To evaluate the association between egg consumption and risk of non-alcoholic fatty liver disease (NAFLD) development.

Methods: This case-control study was conducted on individuals who were referred to two hepatology clinics in Tehran, Iran in 2015. The study included 169 patients with NAFLD and 782 controls. Egg consumption was estimated using a validated food frequency questionnaire. The participants were categorized according to the frequency of their egg consumption during the previous year: Less than two eggs per week, two to three eggs per week, and four or more eggs per week.

Results: In the crude model, participants who consumed 2 to 3 eggs per week, were 3.56 times more likely to have NAFLD in comparison to those who consumed less than 2 eggs per week (OR: 3.56; 95%CI: 2.35-5.31). Adjustment for known risk factors of NAFLD strengthened this significant association so that individuals have consumed two to three eggs per week had 3.71 times higher risk of NAFLD than those who have eaten less than two eggs per week (OR: 3.71; 95%CI: 1.91, 7.75).

Conclusion: Our data indicate that higher egg consumption in common amount of usage is associated with higher risk of NAFLD.

Keywords: Diet; Dietary cholesterol; Egg; Non-alcoholic fatty liver disease.

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Conflict of interest statement

Conflict-of-interest statement: None of the authors had any personal or financial conflicts of interest to report.

Figures

Figure 1
Figure 1
Multivariate-adjusted odds ratio for non-alcoholic fatty liver diseaseaccording to egg consumption. A: Crude model; B: Model 2, multivariate adjusted for age and energy intake; C: Model 3, further controlled for, body mass index, history of diabetes and smoking; D: Model 4, additionally adjusted for physical activity, and gender. Data are presented as the odds ratio (95%CI).
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