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Review
. 2010 May-Jun;21(3):148-53.

Vitamin E and allergic contact dermatitis

Payman Kosari  1 , Ali Alikhan, Mary Sockolov, Steven R Feldman
Affiliations
  • PMID: 20487657
Review

Vitamin E and allergic contact dermatitis

Payman Kosari et al. Dermatitis. 2010 May-Jun.

Abstract

Reports of vitamin E-induced allergic contact dermatitis (ACD) and frequent use of vitamin-E derivatives (tocopherol, tocopheryl linoleate, tocopherol acetate, etc) in skin care products deserves further investigation into tolerability and suitability of vitamin E in skin care preparations. A PubMed search was conducted to review the prevalence of vitamin E-induced ACD. It revealed 931 cases of vitamin E-induced ACD mainly from one large study. There were no reported deaths and only three patients required hospitalization for treatment. It appears that vitamin E-induced ACD is an uncommon phenomenon; incidence is low despite its widespread use in skin care products. Given its antioxidant and photoprotective properties, vitamin E should remain an ingredient in skin care products.

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