doi: 10.1016/j.bmcl.2005.05.092.
Interaction of chiral MS-245 analogs at h5-HT6 receptors
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- PMID: 15990303
- DOI: 10.1016/j.bmcl.2005.05.092
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Interaction of chiral MS-245 analogs at h5-HT6 receptors
Bioorg Med Chem Lett.
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Abstract
Optically active pyrrolidinylmethylindole analogs related in structure to the benzenesulfonyltryptamine 5-HT(6) receptor antagonist MS-245 were evaluated and their R-isomers were found to bind with affinity higher than their S-enantiomers.
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