Hey everyone! Long time no see! Today we'll be learning about heme synthesis. The biosynthesis of heme mnemonic 1. The heme ring system is synthesized from glycine and succinyl-CoA in the mitochondria. d-Aminolevulinate Synthase (ALA Synthase, ALAS) is the rate-limiting step. Pyridoxal phosphate is the coenzyme. Mnemonic: "Alas! Mighty dracula sucks blood with glistening phoshorous teeth." Alas! (ALA synthetase enzyme) Mighty (Mitochondria) Dracula (d-ALA) Sucking (Succinyl CoA) Blood (Heme...