GPR161

G protein-coupled receptor 161
Identifiers
Symbols	GPR161 ; RE2
External IDs	OMIM: 612250 MGI: 2685054 HomoloGene: 17824 IUPHAR: 141 GeneCards: GPR161 Gene
Gene ontology Molecular function • G-protein coupled receptor activity • G-protein coupled amine receptor activity Cellular component • integral component of plasma membrane • endocytic vesicle membrane • recycling endosome • ciliary membrane • primary cilium Biological process • G-protein coupled receptor signaling pathway • multicellular organismal development • sensory perception of chemical stimulus • regulation of smoothened signaling pathway • positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway • positive regulation of cAMP biosynthetic process • negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	23432	240888
Ensembl	ENSG00000143147	ENSMUSG00000040836
UniProt	Q8N6U8	B2RPY5
RefSeq (mRNA)	NM_001267609	NM_001081126
RefSeq (protein)	NP_001254538	NP_001074595
Location (UCSC)	Chr 1: 168.08 – 168.14 Mb	Chr 1: 165.3 – 165.33 Mb
PubMed search	[1]	[2]

G-protein coupled receptor 161 is a protein that in humans is encoded by the GPR161 gene.

Further reading

• Schöneberg T, Schulz A, Gudermann T (2002). "The structural basis of G-protein-coupled receptor function and dysfunction in human diseases". Rev. Physiol. Biochem. Pharmacol. Reviews of Physiology, Biochemistry and Pharmacology 144: 143–227. doi:10.1007/BFb0116587. ISBN 978-3-540-42814-5. PMID 11987825. 
• Raming K, Konzelmann S, Breer H (1999). "Identification of a novel G-protein coupled receptor expressed in distinct brain regions and a defined olfactory zone". Recept. Channels 6 (2): 141–51. PMID 9932290. 
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. 
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. 
• Gregory SG, Barlow KF, McLay KE; et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.